Terpenoid Metabolic Engineering in Photosynthetic Microorganisms

Metabolic Engineering of Synechocystis sp. PCC 6803 for Terpenoid Production

Englund, E. 2016. Metabolic Engineering of Synechocystis sp. PCC 6803 for Terpenoid Production. Digital Comprehensive Summaries of Uppsala Dissertations from the Faculty of Science and Technology 1455. 63 pp. Uppsala: Acta Universitatis Upsaliensis. ISBN 978-91-554-9761-3. In the Paris Agreement from 2015, nations agreed to limit the effects of global warming to well below 2°C. To be able to re...

Metabolic flux analysis and metabolic engineering of microorganisms.

Recent advances in metabolic flux analysis including genome-scale constraints-based flux analysis and its applications in metabolic engineering are reviewed. Various computational aspects of constraints-based flux analysis including genome-scale stoichiometric models, additional constraints used for the improved accuracy, and several algorithms for identifying the target genes to be manipulated...

Advances in Metabolic Engineering of Cyanobacteria for Photosynthetic Biochemical Production

Engineering cyanobacteria into photosynthetic microbial cell factories for the production of biochemicals and biofuels is a promising approach toward sustainability. Cyanobacteria naturally grow on light and carbon dioxide, bypassing the need of fermentable plant biomass and arable land. By tapping into the central metabolism and rerouting carbon flux towards desirable compound production, cyan...

Photosynthetic Microorganisms and Valuable Products

Metabolic engineering of microorganisms: general strategies and drug production.

Many drugs and drug precursors found in natural organisms are rather difficult to synthesize chemically and to extract in large amounts. Metabolic engineering is playing an increasingly important role in the production of these drugs and drug precursors. This is typically achieved by establishing new metabolic pathways leading to the product formation, and enforcing or removing the existing met...